Speaker
Description
Our study aims to optimize slow-release formulations for agricultural use by employing biodegradable materials. The tablet contains salicylic acid (100 mg) as the active ingredient, three excipients: phosphorylated starch (PS), polyvinyl alcohol (PVA), and polyvinyl acetate as a membrane to regulate the release. The findings demonstrate that phosphorylated starch significantly enhances water retention, with water uptake increasing from 253 mg to 384 mg as PS content rises from 0 to 50 mg per tablet, representing a 52% increase. Experiments conducted at different pH levels (1.64 and 7.1) and with varying numbers of coating layers (1 to 3) revealed a complex two-step release mechanism that could not be fully described by traditional kinetic models (Higuchi and Korsmeyer–Peppas). This formulation shows strong potential for agricultural applications, such as slow-release fertilizers and plant stimulants, offering prolonged activity, reduced environmental impact, and improved plant resistance to stress and pathogens.
